![]() A dry eye diagnosis then requires a positive score on one of two specific symptom questionnaires, followed by at least one positive clinical sign indicating a reduced non-invasive tear break-up time (a measure of tear film stability), an elevated or a large inter-eye disparity in osmolarity (tear saltiness), or ocular surface damage indicated by dye staining. The most common cause of evaporative dry eye is meibomian gland dysfunction.Ī recommended sequence of tests for the diagnosis of dry eye disease first utilizes questions to exclude conditions that mimic dry eye. ![]() The core mechanism of dry eye disease is evaporation-induced tear hyperosmolarity (higher salt concentration than normal), which is the trigger for a cascade of events leading to eye surface damage and inflammation. Two forms of dry eye are recognized, aqueous deficient resulting from reduced tear secretion, and evaporative resulting from excessive tear evaporation. reading, driving, use of digital devices), sleep deprivation, reduced energy, poor general health, and often depression. Moderate to severe dry eye can be life-altering and may be associated with eye pain, limitations in performing daily activities (e.g. This symptomatic disease is characterized by an unstable and a more concentrated (termed hyperosmolar) tear film, which leads to increased inflammation and damage to eye structures and nerves. GORDON RESEARCH CONFERENCE: THE BIOLOGY AND PATHOBIOLOGY OF THE CORNEAĭry eye disease affects millions of people throughout the world and is one of the most common reasons for patients to seek eye care.TFOS CLAES DOHLMAN CONFERENCE AWARD WINNERS.TFOS DEWS REPORT OF THE DRY EYE WORKSHOP.TFOS INTERNATIONAL WORKSHOP ON MEIBOMIAN GLAND DYSFUNCTION.LIFESTYLE EPIDEMIC: OCULAR SURFACE DISEASE.INVITATION TO TFOS LIFESTYLE REPORT PRESENTATIONS.EUROPEAN TFOS AMBASSADOR MEETING - 2019.TFOS LIVE/VIRTUAL MEETING IN ROME, ITALY - 2020.TFOS GLAUCOMA / OCULAR SURFACE DISEASE MEETING - 2022.
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